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Calf Serum (Bovine Calf Serum, BCS) is collected from cattle between 14 days and 12 months old. Calf Serum contains more immunoglobulins than Fetal Bovine Serum and has increased protein content. BCS is a cost-effective substitute for Fetal Bovine Serum in promoting the growth of various mammalian cell lines.

BCS can be offered with treatments such as gamma irradiation or heat inactivation upon request. Gamma irradiation involves the inactivation of contaminants through irradiation with a maximum dose of 38.7 kGy. This gentle irradiation is less likely to affect serum quality while maintaining the inactivation of contaminants. Heat inactivation involves heating the serum in a shaking water bath at +56°C for 30 minutes, leading to the inactivation of the complement system, antibodies, and other active enzymes.