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Low-toxicity DNA transfection reagent

GENIUS DNA Transfection Reagent shows very low cytotoxicity, compared to lipid-based or other polymer-based transfection reagents, as it is a sterile solution of a cationic polymer in water. The polymer forms compact, stable, positively charged complexes with DNA. These complexes protect DNA from degradation and facilitate gene delivery into various eukaryotic cells.

DNA transfection can be performed in the presence or absence of serum. In addition, it is also compatible with antibiotics, resulting in a fast and simple cell tranfection protocol without media changes.

High transfection efficiencies in various cell types

 GENIUS DNA Transfection Reagent is ideal for high-efficiency transfection of various adherent cells including HeLa, HEK-293, NIH-3T3, CHO, Cos and Jurkat cells. Adherent primary cells can also be efficiently tranfected.

Lower cost transfection reagent compared to lipotransfections

With GENIUS DNA transfection reagent you can forget about lipotransfections for optimal gene delivery. GENIUS overcomes any drawbacks of traditional lipofection at a much lower price: GENIUS costs only  € 1,07 per transfection (based on 6-well plate assays).